Zafirlukast: the first leukotriene-receptor antagonist approved for the treatment of asthma.

@article{Kelloway1997ZafirlukastTF,
  title={Zafirlukast: the first leukotriene-receptor antagonist approved for the treatment of asthma.},
  author={Judy Shepard Kelloway},
  journal={The Annals of pharmacotherapy},
  year={1997},
  volume={31 9},
  pages={1012-21}
}
OBJECTIVE To review the pharmacology, pharmacokinetics, clinical efficacy, and adverse effects of zafirlukast. Therapeutic issues regarding the use of a leukotriene-receptor antagonist as prophylactic antiinflammatory therapy for asthma are also discussed. DATA SOURCES A MEDLINE search was conducted to identify pertinent literature, including preclinical trials, clinical trials, and reviews. Pharmacokinetic and dosing information were abstracted from the product labeling. STUDY SELECTION… CONTINUE READING

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