ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway

  title={ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway},
  author={Yongqing Li and Dan Yang and Yan Bai and Xiao-yang Mo and Wen Huang and Wuzhou Yuan and Zhaochu Yin and Yun Deng and Oleg N. Murashko and Yuequn Wang and Xiongwei Fan and Chuanbing Zhu and Karen Ocorr and Rolf Bodmer and Xiushan Wu},
  journal={Molecular and Cellular Biochemistry},
Cardiac differentiation involves a cascade of coordinated gene expression that regulates cell proliferation and matrix protein formation in a defined temporal-spatial manner. Zinc finger-containing transcription factors have been implicated as critical regulators of multiple cardiac-expressed genes, and are thought to be important for human heart development and diseases. Here, we have identified and characterized a novel zinc finger gene named ZNF418 from a human embryo heart cDNA library. The… CONTINUE READING
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A rapid method of extracting total RNA from embryo tissues

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