ZFX Controls the Self-Renewal of Human Embryonic Stem Cells

@inproceedings{Harel2012ZFXCT,
  title={ZFX Controls the Self-Renewal of Human Embryonic Stem Cells},
  author={Sivan Harel and Edmund Y. Tu and Stuart A. Weisberg and Manuel Esquilin and Stuart M. Chambers and Becky Jie Liu and Christian T. Carson and Lorenz P Studer and Boris Reizis and Mark J. Tomishima},
  booktitle={PloS one},
  year={2012}
}
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) offer great promise in regenerative medicine and disease modeling due to their unlimited self-renewal and broad differentiation capacity. There is evidence that the growth properties and critical signaling pathways differ between murine and human ESCs; therefore, it is essential to perform functional studies to test the putatively conserved mechanisms of pluripotent stem cell self-renewal between species. Previously, we… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 26 REFERENCES

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2010
VIEW 1 EXCERPT

Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2010
VIEW 1 EXCERPT

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