ZEITLUPE Encodes a Novel Clock-Associated PAS Protein from Arabidopsis

@article{Somers2000ZEITLUPEEA,
  title={ZEITLUPE Encodes a Novel Clock-Associated PAS Protein from Arabidopsis},
  author={David E. Somers and Thomas F. Schultz and M Milnamow and Steve A. Kay},
  journal={Cell},
  year={2000},
  volume={101},
  pages={319-329}
}
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Molecular and genetic analysis of a novel f-box protein, seitlupe, in the arabidopsis circadian clock
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The primary focus of this dissertation is to characterize the light-regulated proteolytic pathway mediated by ZTL, and identified two post-translational regulatory events which are shared by four PRR members (PRR1/3/5/7): phosphorylation and proteasome-dependent protein turn over.
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It is demonstrated that CCA1 and LHY bind to the evening element motif in the LUX promoter, which strongly suggests that these proteins repress LUX expression, as they do TOC1, and the data are consistent with LUX being necessary for activation of CCA 1 and L HY expression.
tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator.
Clock-associated genes in Arabidopsis: a family affair.
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  • Biology
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 2001
TLDR
The ZEITLUPE and TOC1 loci were cloned and each was found to be part of two separate, larger gene families with intriguing domain structures, suggesting that they play a role in a novel light-regulated ubiquitination mechanism.
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Results suggest that AGL6 plays a potential role in the regulation of the circadian clock by regulating ZTL mRNA level in Arabidopsis.
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Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog.
TLDR
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants and it is shown that TOC1 controls photoperiodic flowering response through clock function.
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References

SHOWING 1-10 OF 141 REFERENCES
FKF1, a Clock-Controlled Gene that Regulates the Transition to Flowering in Arabidopsis
Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression.
  • R. Green, E. Tobin
  • Environmental Science, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1999
TLDR
The results indicate that CCA1 is an important clock-associated protein involved in circadian regulation of gene expression that affects the circadian expression of all four clock-controlled genes that the authors examined.
The short-period mutant, toc1-1, alters circadian clock regulation of multiple outputs throughout development in Arabidopsis thaliana.
TLDR
A new set of circadian clock-controlled phenotypes for Arabidopsis thaliana are reported, consistent with the likelihood that TOC1 codes for an oscillator component rather than for an element of an input signaling pathway, and indicate that T OC1 acts on or within the clock independently of light input.
Attenuation of phytochrome A and B signaling pathways by the Arabidopsis circadian clock.
TLDR
It is demonstrated that persistent Pfr signaling occurs in red light-pulsed etiolated seedlings, which suggests that the circadian clock antagonizes Pfr-mediated signal transduction.
Constitutive Expression of the CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) Gene Disrupts Circadian Rhythms and Suppresses Its Own Expression
COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility.
TLDR
The coi1 mutation defines an Arabidopsis gene required for response to jasmonates, which regulate defense against insects and pathogens, wound healing, and pollen fertility, and appears to function by targeting repressor proteins for removal by ubiquitination.
double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation
The late elongated hypocotyl Mutation of Arabidopsis Disrupts Circadian Rhythms and the Photoperiodic Control of Flowering
Circadian clock mutants in Arabidopsis identified by luciferase imaging
TLDR
The cycling bioluminescence of Arabidopsis plants carrying a firefly luciferase fusion construct was used to identify mutant individuals with aberrant cycling patterns, and a semidominant short-period mutation, toc1, was mapped to chromosome 5.
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
...
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