ZEB proteins link cell motility with cell cycle control and cell survival in cancer.

@article{Browne2010ZEBPL,
  title={ZEB proteins link cell motility with cell cycle control and cell survival in cancer.},
  author={Gareth J. Browne and Abdulkadir Emre Sayan and Eugene Tulchinsky},
  journal={Cell cycle},
  year={2010},
  volume={9 5},
  pages={886-91}
}
Epithelial mesenchymal transitions (EMT), the generation of motile mesenchymal cells from epithelial sheets, are differentiation programs which take place at several critical steps of embryonic development and in metastatic cancer. Recent data have shown that the transcription factors which are master regulators of EMT also regulate cell cycle progression, apoptosis and senescence. In light of these new observations, the role of these factors in human cancer may be broader than previously… CONTINUE READING

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