ZD1839: targeting the epidermal growth factor receptor in cancer therapy.

@article{Herbst2002ZD1839TT,
  title={ZD1839: targeting the epidermal growth factor receptor in cancer therapy.},
  author={Roy S. Herbst},
  journal={Expert opinion on investigational drugs},
  year={2002},
  volume={11 6},
  pages={837-49}
}
  • Roy S. Herbst
  • Published 2002 in Expert opinion on investigational drugs
The erbB family of receptors, which includes the epidermal growth factor receptor, has been widely implicated in promoting proliferation of malignant cells. The critical role played by epidermal growth factor receptor in cancer has resulted in extensive research for selective inhibitors of the epidermal growth factor receptor signalling pathway. Selective small molecule epidermal growth factor receptor-tyrosine kinase inhibitors, such as ZD1839 (Iressa), block signal transduction pathways… CONTINUE READING

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