Z/AP, a double reporter for cre-mediated recombination.

  title={Z/AP, a double reporter for cre-mediated recombination.},
  author={Corrinne G. Lobe and Karen E. Koop and W Kreppner and Hilda Lomel{\'i} and Marina Gertsenstein and Andras D Nagy},
  journal={Developmental biology},
  volume={208 2},
The Cre/loxP site-specific recombination system combined with embryonic stem cell-mediated technologies has greatly expanded our capability to address normal and disease development in mammals using genetic approaches. The success of this emerging technology hinges on the production of Cre-expressing transgenic lines that provide cell type-, tissue-, or developmental stage-specific recombination between loxP sites placed in the genome. Here we describe and characterize the production of a… CONTINUE READING
Highly Influential
This paper has highly influenced 39 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.
239 Citations
46 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 239 extracted citations


Publications referenced by this paper.
Showing 1-10 of 46 references

Production of completely ES cell - derived fetuses

  • J. Rossant
  • “ Practical Approach Series : Gene Targeting : A…
  • 1993
Highly Influential
4 Excerpts

Tissue specific knock-out of the Pig-a gene revealed important roles of GPIanchored proteins in skin development

  • M. Tarutani, S. Itami, +5 authors J. Takeda
  • Proc. Natl. Acad. Sci. USA
  • 1997
2 Excerpts

Similar Papers

Loading similar papers…