Yttrium (amidate) complexes for catalytic C-N bond formation. Rapid, room temperature amidation of aldehydes.

@article{Thomson2012YttriumC,
  title={Yttrium (amidate) complexes for catalytic C-N bond formation. Rapid, room temperature amidation of aldehydes.},
  author={Jaclyn A Thomson and Laurel L Schafer},
  journal={Dalton transactions},
  year={2012},
  volume={41 26},
  pages={7897-904}
}
Yttrium (amidate) precatalysts are highly active for the mild amidation of aldehydes with amines. Reactions occur at room temperature within 5 min in up to 98% isolated yield. These rare-earth systems are effective for this transformation in the absence of supplementary heat, light, base, or oxidants. The reaction proceeds with functionalized amines and/or aldehydes. A comparison of various amidate precatalysts in combination with reaction monitoring suggests that the targeted amide products… CONTINUE READING

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AldehydesNo subtypeAmines
Yttrium ( amidate ) precatalysts are highly active for the mild amidation of aldehydes with amines .
The reaction proceeds with functionalized amines and/or aldehydes .
AminesNo subtypeAldehydes
Yttrium ( amidate ) precatalysts are highly active for the mild amidation of aldehydes with amines .
The reaction proceeds with functionalized amines and/or aldehydes .
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