Young hippocampal neurons are critical for recent and remote spatial memory in adult mice.

@article{Goodman2010YoungHN,
  title={Young hippocampal neurons are critical for recent and remote spatial memory in adult mice.},
  author={Trudy Goodman and St{\'e}phanie Trouche and Isabelle Massou and Laure Verret and Meike Zerwas and Pascal Roullet and Christine Rampon},
  journal={Neuroscience},
  year={2010},
  volume={171 3},
  pages={769-78}
}
New granule cells are continuously generated throughout adulthood in the mammalian hippocampus. These newly generated neurons become functionally integrated into existing hippocampal neuronal networks, such as those that support retrieval of remote spatial memory. Here, we sought to examine whether the contribution of newly born neurons depends on the type of learning and memory task in mice. To do so, we reduced neurogenesis with a cytostatic agent and examined whether depletion of young… CONTINUE READING