Yolk-shell hybrid nanoparticles with magnetic and pH-sensitive properties for controlled anticancer drug delivery.

@article{Li2013YolkshellHN,
  title={Yolk-shell hybrid nanoparticles with magnetic and pH-sensitive properties for controlled anticancer drug delivery.},
  author={Shunxing Li and Jianzhong Zheng and Dejian Chen and Yijin Wu and Wuxiang Zhang and Fengying Zheng and Jing Cao and Heran Ma and Yaling Liu},
  journal={Nanoscale},
  year={2013},
  volume={5 23},
  pages={11718-24}
}
A facile and effective way for the preparation of nano-sized Fe3O4@graphene yolk-shell nanoparticles via a hydrothermal method is developed. Moreover, the targeting properties of the materials for anticancer drug (doxorubicin hydrochloride) delivery are investigated. Excitingly, these hybrid materials possess favorable dispersibility, good superparamagnetism (the magnetic saturation value is 45.740 emu g(-1)), high saturated loading capacity (2.65 mg mg(-1)), and effective loading (88.3%). More… CONTINUE READING