Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages.

@article{Joo2007YinY1,
  title={Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages.},
  author={Myungsoo Joo and Jeffrey G Wright and Ning Ning Hu and Ruxana T. Sadikot and Gye Young Park and Timothy S. Blackwell and John W Christman},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2007},
  volume={292 5},
  pages={L1219-26}
}
Expression of cyclooxygenase-2 (COX-2) is associated with the pathogenesis of inflammation and various cancers, including lung cancer. Yin Yang 1 (YY1) is a zinc-finger transcription factor that interacts with histone acetyltransferases and deacetylases for its transcriptional activity and also is involved in inflammation and tumorigenesis. We investigated whether YY1 regulates COX-2 expression. We located a possible YY1 binding site proximal to the transcription initiation site of the COX-2… CONTINUE READING
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Yin Yang 1 ( YY1 ) is a zinc - finger transcription factor that interacts with histone acetyltransferases and deacetylases for its transcriptional activity and also is involved in inflammation and tumorigenesis .
Yin Yang 1 ( YY1 ) is a zinc - finger transcription factor that interacts with histone acetyltransferases and deacetylases for its transcriptional activity and also is involved in inflammation and tumorigenesis .
Yin Yang 1 ( YY1 ) is a zinc - finger transcription factor that interacts with histone acetyltransferases and deacetylases for its transcriptional activity and also is involved in inflammation and tumorigenesis .
Yin Yang 1 ( YY1 ) is a zinc - finger transcription factor that interacts with histone acetyltransferases and deacetylases for its transcriptional activity and also is involved in inflammation and tumorigenesis .
Expression of cyclooxygenase-2 ( COX-2 ) is associated with the pathogenesis of inflammation and various cancers , including lung cancer .
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