Yesterday's polyploids and the mystery of diploidization

@article{Wolfe2001YesterdaysPA,
  title={Yesterday's polyploids and the mystery of diploidization},
  author={K. Wolfe},
  journal={Nature Reviews Genetics},
  year={2001},
  volume={2},
  pages={333-341}
}
  • K. Wolfe
  • Published 2001
  • Medicine, Biology
  • Nature Reviews Genetics
  • Thirty years after Susumu Ohno proposed that vertebrate genomes are degenerate polyploids, the extent to which genome duplication contributed to the evolution of the vertebrate genome, if at all, is still uncertain. Sequence-level studies on model organisms whose genomes show clearer evidence of ancient polyploidy are invaluable because they indicate what the evolutionary products of genome duplication can look like. The greatest mystery is the molecular basis of diploidization, the… CONTINUE READING

    Figures and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    The amphioxus genome and the evolution of the chordate karyotype
    • 1,371
    • PDF
    Two Rounds of Whole Genome Duplication in the Ancestral Vertebrate
    • 1,178
    • PDF
    Evolution by gene duplication: an update
    • 1,730
    • PDF
    Widespread Paleopolyploidy in Model Plant Species Inferred from Age Distributions of Duplicate Genes
    • 960
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 78 REFERENCES