Yessotoxin in mussels of the northern Adriatic Sea.

  title={Yessotoxin in mussels of the northern Adriatic Sea.},
  author={P. Ciminiello and E. Fattorusso and M. Forino and S. Magno and R. Poletti and M. Satake and R. Viviani and T. Yasumoto},
  journal={Toxicon : official journal of the International Society on Toxinology},
  volume={35 2},
This study investigated the composition of diarrhoetic shellfish toxins in the hepatopancreas of mussels from the northern Adriatic Sea. The major toxins were shown to be yessotoxin, identified by its chromatographic properties and spectral data, and okadaic acid, detected both by fluorometric high-performance liquid chromatography and by comparison of its spectral properties with those of an authentic sample. 
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The diarrhetic shellfish toxin composition in the hepatopancreas of mussels from the northern Adriatic sea was investigated. The major toxins were shown to be yessotoxin (YTX), homoyessotoxinExpand
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As part of an effort to identify the common pharmacophore for the toxins, Monte Carlo methods were used to generate conformational models of the polyether ladder toxin brevetoxin B which shows significant flexibility at the juncture of the two 7-membered rings. Expand
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