Yersinia enterocolitica invasin protein triggers IL-8 production in epithelial cells via activation of Rel p65-p65 homodimers.

@article{Schulte2000YersiniaEI,
  title={Yersinia enterocolitica invasin protein triggers IL-8 production in epithelial cells via activation of Rel p65-p65 homodimers.},
  author={Roberta Schulte and Guntram Grassl and S Preger and Sabine Fessele and Christoph A Jacobi and Martin Schaller and Peter Jon Nelson and I. Autenrieth},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2000},
  volume={14 11},
  pages={1471-84}
}
Enteropathogenic Yersinia bacteria trigger the production of the proinflammatory chemokine IL-8, an important chemokine for the recruitment of polymorphonuclear leukocytes (PMN). Yersinia is resistant to phagocytosis by PMN, and the recruitment of these cells is thought to be part of a pathogenic strategy of Yersinia to establish infection by allowing the pathogen to gain access to, and disseminate within, host tissue. We report here that Yersinia expressing the outer membrane protein invasin… CONTINUE READING
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