Yeast ribosomal protein L1 is required for the stability of newly synthesized 5S rRNA and the assembly of 60S ribosomal subunits.

@article{Deshmukh1993YeastRP,
  title={Yeast ribosomal protein L1 is required for the stability of newly synthesized 5S rRNA and the assembly of 60S ribosomal subunits.},
  author={Minal S. Deshmukh and Yi Fang Tsay and Amanda G. Paulovich and John L. Woolford},
  journal={Molecular and cellular biology},
  year={1993},
  volume={13 5},
  pages={
          2835-45
        }
}
Ribosomal protein L1 from Saccharomyces cerevisiae binds 5S rRNA and can be released from intact 60S ribosomal subunits as an L1-5S ribonucleoprotein (RNP) particle. To understand the nature of the interaction between L1 and 5S rRNA and to assess the role of L1 in ribosome assembly and function, we cloned the RPL1 gene encoding L1. We have shown that RPL1 is an essential single-copy gene. A conditional null mutant in which the only copy of RPL1 is under control of the repressible GAL1 promoter… CONTINUE READING
Highly Cited
This paper has 94 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 57 extracted citations

Functional features of the C-terminal region of yeast ribosomal protein L5

Molecular Genetics and Genomics • 2008
View 16 Excerpts
Method Support
Highly Influenced

95 Citations

051015'95'00'06'12'18
Citations per Year
Semantic Scholar estimates that this publication has 95 citations based on the available data.

See our FAQ for additional information.