Yeast lacking superoxide dismutase. Isolation of genetic suppressors.


Null mutants of superoxide dismutase (SOD) in Saccharomyces cerevisiae are associated with a number of biochemical defects. In addition to being hypersensitive to oxygen toxicity, strains containing deletions in both the SOD1 (encoding Cu/Zn-SOD) and SOD2 (encoding Mn-SOD) genes are defective in sporulation, are associated with a high mutation rate, and are… (More)


Cite this paper

@article{Liu1992YeastLS, title={Yeast lacking superoxide dismutase. Isolation of genetic suppressors.}, author={Xian Fang Liu and Ilya Elashvili and Edith Butler Gralla and Joan Selverstone Valentine and Paula Lapinskas and Valeria C Culotta}, journal={The Journal of biological chemistry}, year={1992}, volume={267 26}, pages={18298-302} }