Yeast-generated virus-like particles as antigens for detection of human bocavirus 1–4 specific antibodies in human serum

Abstract

Human bocaviruses (HBoV) are non-enveloped, single-stranded DNA viruses, classified into the genus Bocavirus in the family Parvoviridae. Self-assembled virus-like particles (VLPs) composed of the major capsid protein VP2 of HBoV1–4 and mosaic VLPs composed of both VP2 and VP1 capsid proteins of HBoV1 were generated in yeast Saccharomyces cerevisiae and used… (More)
DOI: 10.1007/s00253-016-7336-8

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