Yeast flavin-containing monooxygenase is induced by the unfolded protein response.

@article{Suh2000YeastFM,
  title={Yeast flavin-containing monooxygenase is induced by the unfolded protein response.},
  author={Jun Kyu Suh and Jon D. Robertus},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 1},
  pages={121-6}
}
Flavin-containing monooxygenase from yeast (yFMO) carries out the O(2)- and NADPH-dependent oxidation of biological thiols, including oxidizing glutathione to glutathione disulfide. FMO provides a large fraction of the oxidizing necessary for proper folding of disulfide bond-containing proteins; deletion of the enzyme reduces proper folding of endogenous carboxypeptidase Y by about 40%. The enzyme is not essential to cell viability because other enzymes can generate a significant fraction of… CONTINUE READING