Yeast cystathionine beta-synthase is a pyridoxal phosphate enzyme but, unlike the human enzyme, is not a heme protein.

@article{Jhee2000YeastCB,
  title={Yeast cystathionine beta-synthase is a pyridoxal phosphate enzyme but, unlike the human enzyme, is not a heme protein.},
  author={Kwang Hwan Jhee and P. Mcphie and Edith Wilson Miles},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 16},
  pages={
          11541-4
        }
}
Our studies of cystathionine beta-synthase from Saccharomyces cerevisiae (yeast) are aimed at clarifying the cofactor dependence and catalytic mechanism and obtaining a system for future investigations of the effects of mutations that cause human disease (homocystinuria or coronary heart disease). We report methods that yielded high expression of the yeast gene in Escherichia coli and of purified yeast cystathionine beta-synthase. The absorption and circular dichroism spectra of the homogeneous… CONTINUE READING

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