Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation.

@article{Black2007YeastAS,
  title={Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation.},
  author={Paul N Black and Concetta C DiRusso},
  journal={Biochimica et biophysica acta},
  year={2007},
  volume={1771 3},
  pages={286-98}
}
Acyl-CoA synthetases (ACSs) are a family of enzymes that catalyze the thioesterification of fatty acids with coenzymeA to form activated intermediates, which play a fundamental role in lipid metabolism and homeostasis of lipid-related processes. The products of the ACS enzyme reaction, acyl-CoAs, are required for complex lipid synthesis, energy production via beta-oxidation, protein acylation and fatty-acid dependent transcriptional regulation. ACS enzymes are also necessary for fatty acid… CONTINUE READING

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