Yeast Oxidosqualene Cyclase (Erg7p) Is a Major Component of Lipid Particles*

@article{Milla2002YeastOC,
  title={Yeast Oxidosqualene Cyclase (Erg7p) Is a Major Component of Lipid Particles*},
  author={Paola Milla and Karin Athenstaedt and Franca Viola and Simonetta Oliaro-Bosso and Sepp D. Kohlwein and Günther Daum and Gianni Balliano},
  journal={The Journal of Biological Chemistry},
  year={2002},
  volume={277},
  pages={2406 - 2412}
}
Oxidosqualene cyclase of the yeast encoded by the ERG7 gene converts oxidosqualene to lanosterol, the first cyclic component of sterol biosynthesis. In a previous study (Athenstaedt, K., Zweytick, D., Jandrositz, A, Kohlwein, S. D., and Daum, G. (1999) J. Bacteriol. 181, 6441–6448), Erg7p was identified as a component of yeast lipid particles. Here, we present evidence that Erg7p is almost exclusively associated with this compartment as shown by analysis of enzymatic activity, Western blot… 

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