Yeast Genome Sequence Ferments New Research

@article{Williams1996YeastGS,
  title={Yeast Genome Sequence Ferments New Research},
  author={Nigel Williams},
  journal={Science},
  year={1996},
  volume={272},
  pages={481 - 481}
}
In simultaneous press conferences in Brussels and Washington, researchers unveiled the complete genome of the most complex organism yet sequenced—brewer's yeast. The 12-million-base sequence, the result of a European Union-funded collaboration of more than 100 laboratories, is the first for a member of the eukaryotes—organisms that, unlike bacteria, have nucleated cells, among them all multicelled animals and plants. The similarities of yeast genes to those of more complex organisms, including… 
View on AAAS
ncbi.nlm.nih.gov
29 Citations
Background Citations
7

29 Citations

Citation Type

Citation Type

Yeasties and beasties: 7 years of genome sequencing
  • K. Thomas
  • Biology, Engineering
    FEBS letters
  • 1996
LESSONS FROM SEQUENCING OF THE GENOME OF A UNICELLULAR CYANOBACTERIUM, SYNECHOCYSTIS SP. PCC6803.
  • H. Kotani, S. Tabata
  • Biology, Engineering
    Annual review of plant physiology and plant molecular biology
  • 1998
The nucleotide sequence of the entire genome of the unicellular cyanobacterium, Synechocystis sp. PCC6803, has been determined. The length of the circular genome was 3,573,480 bp, and a total of 3168…
Rapid Amplification of Uncharacterized Transposon‐tagged DNA Sequences from Genomic DNA
TLDR
This report describes a semi‐random, two‐step PCR protocol, ST‐PCR, which is simpler and more specific than current methods, requiring only genomic DNA and two pairs of PCR primers, and involving two successive PCR reactions.
European collaboration in biotechnology: the molecular analysis of genomes
TLDR
The research presented here suggests that, far from leading to the demise of the traditional small laboratory, these new large-scale collaborative projects are in fact strengthening the small group which will continue to dominate research in molecular biology through interaction with the large groups.
A broad-host-range in vivo pop-out and amplification system for generating large quantities of 50- to 100-kb genomic fragments for direct DNA sequencing.
Yeast homologues of higher eukaryotic TFIID subunits.
TLDR
Yeast TAF61 is significantly larger than its higher eukaryotic homologues, and deletion analysis demonstrates that the evolutionarily conserved, histone-like domain is sufficient and necessary to support viability.
Spreadsheets in molecular biology
TLDR
The specific nucleic acid sequence is decoded into a specific protein sequence, which in turn defines the folded three-dimensional structure and positioning of chemically reactive amino acid side chains on this structure, both of which determine the function of the protein.
Sequence analysis of a nuclear pore complex protein in a lower metazoan: nucleoporin p62 of the coelenterate Hydra vulgaris.
Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion.
TLDR
Alignment of the nine peptide deformylase sequences showed that, in addition to the two above sequences, only a third one, GXGXAAXQ, is strictly conserved, and this motif is located in the active site according to the three-dimensional structure of the E. coli enzyme.
Analysis of the Trypanosoma brucei Genome and Identification and Characterization of a Gene Family Encoding Putative EF-Hand Calcium-Binding Proteins
The flagellum of Trypanosoma brucei contains a family of antigenically related EF-hand calcium-binding proteins which are called the calflagins. Genomic Southern blots indicated that multiple copies…
...
1
2
3
...