Yeast, flies, worms, and fish in the study of human disease.

  title={Yeast, flies, worms, and fish in the study of human disease.},
  author={Iswar K Hariharan and Daniel A. Haber},
  journal={The New England journal of medicine},
  volume={348 24},
The sequencing of the human genome has revealed an almost complete “parts list” for the study of the genetic basis of disease. 1,2 The Online Mendelian Inheritance in Man data base lists more than 1000 human genes that have been implicated in specific diseases. 3 It is likely that within a few years the causative lesion in most diseases that result from a mutation in a single gene will have been characterized, and geneticists are using sophisticated methods to track genes in polygenic diseases… CONTINUE READING

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