YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.

@article{Purta2008YbeAIT,
  title={YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.},
  author={Elzbieta Purta and Katarzyna H. Kaminska and Joanna M. Kasprzak and Janusz M. Bujnicki and S. Douthwaite},
  journal={RNA},
  year={2008},
  volume={14 10},
  pages={2234-44}
}
Pseudouridines in the stable RNAs of Bacteria are seldom subjected to further modification. There are 11 pseudouridine (Psi) sites in Escherichia coli rRNA, and further modification is found only at Psi1915 in 23S rRNA, where the N-3 position of the base becomes methylated. Here, we report the identity of the E. coli methyltransferase that specifically catalyzes methyl group addition to form m(3)Psi1915. Analyses of E. coli rRNAs using MALDI mass spectrometry showed that inactivation of the… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…