YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress.

@article{Goranov2009YabAOB,
  title={YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress.},
  author={Alexi I. Goranov and Adam M Breier and Houra Merrikh and Alan D Grossman},
  journal={Molecular microbiology},
  year={2009},
  volume={74 2},
  pages={454-66}
}
yabA encodes a negative regulator of replication initiation in Bacillus subtilis and homologues are found in many other gram-positive species. YabA interacts with the beta-processivity clamp (DnaN) of DNA polymerase and with the replication initiator and transcription factor DnaA. Because of these interactions, YabA has been proposed to modulate the… CONTINUE READING