YMDD motif variants in inactive hepatitis B carriers detected by Inno-Lipa HBV DR assay.

@article{Akarsu2006YMDDMV,
  title={YMDD motif variants in inactive hepatitis B carriers detected by Inno-Lipa HBV DR assay.},
  author={Mesut Akarsu and Aylin Sengonul and Ethem Tankurt and Ayça Arzu Sayiner and Omer Selahattin Topalak and Hale Akpinar and Yusuf Hakan Abacioğlu},
  journal={Journal of gastroenterology and hepatology},
  year={2006},
  volume={21 12},
  pages={1783-8}
}
INTRODUCTION Mutations of hepatitis B virus (HBV) polymerase, especially occurring at the highly conserved YMDD region, are related to resistance to lamivudine. Although these mutations are frequently secondary to lamivudine use, they can also occur naturally. The aim of the present study was to determine the prevalence of YMDD variants that exist naturally in patients who are inactive HBV carriers. METHODS Seventy-one adult inactive HBV carriers were studied. All of the patients were… CONTINUE READING

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