YKL-40 protein expression is not a prognostic marker in patients with primary breast cancer

@article{Roslind2007YKL40PE,
  title={YKL-40 protein expression is not a prognostic marker in patients with primary breast cancer},
  author={Anne Roslind and Ann Soegaard Knoop and Maj-Britt Jensen and Julia Sidenius Johansen and Dorte Lisbet Nielsen and Paul A. Price and Eva Balslev},
  journal={Breast Cancer Research and Treatment},
  year={2007},
  volume={112},
  pages={275-285}
}
YKL-40 is a new biomarker in serum with a prognostic value in several localized and metastatic malignancies. The current knowledge regarding the biological functions of YKL-40 in cancer links YKL-40 to increased aggressiveness of the tumor. Utilizing tissue microarrays, YKL-40 protein expression in tumor tissue was assessed by immunohistochemistry in a cohort of 630 high-risk breast cancer patients with a median estimated potential follow-up time of 10 and 13 years for disease-free (DFS) and… CONTINUE READING
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