YB-1 protein: functions and regulation.

  title={YB-1 protein: functions and regulation.},
  author={Dmitry N. Lyabin and I. A. Eliseeva and Lev P. Ovchinnikov},
  journal={Wiley interdisciplinary reviews. RNA},
  volume={5 1},
The Y-box binding protein 1 (YB-1, YBX1) is a member of the family of DNA- and RNA-binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into a group of intrinsically disordered proteins that do not follow the classical rule 'one protein-one function' but introduce a novel principle stating that a disordered structure suggests many functions. YB-1 participates in a wide variety of DNA/RNA-dependent events, including DNA reparation, pre-mRNA transcription and… CONTINUE READING
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