YAP1 negatively regulates chondrocyte differentiation partly by activating the β-catenin signaling pathway.

@article{Yang2017YAP1NR,
  title={YAP1 negatively regulates chondrocyte differentiation partly by activating the β-catenin signaling pathway.},
  author={Beining Yang and Hua-ling Sun and Fangfang Song and Miao Yu and Yanru Wu and Jiawei Wang},
  journal={The international journal of biochemistry & cell biology},
  year={2017},
  volume={87},
  pages={104-113}
}
YAP1 (Yes-associated protein 1) transcriptional coactivator is a downstream gene of the Hippo signaling pathway, which controls cell proliferation and differentiation. YAP1 plays a significant role in the regulation of cartilage and bone development. However, the molecular mechanism by which YAP1 regulates chondrocyte differentiation remains to be elucidated. Immunofluorescent staining was used to visualize the localization of YAP1 expression in the mouse chondroprogenitor ATDC5 cell line… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-2 of 2 extracted citations

Similar Papers

Loading similar papers…