Y2 receptor expression and inhibition of voltage-dependent Ca2+ influx into rod bipolar cell terminals.

@article{DAngelo2004Y2RE,
  title={Y2 receptor expression and inhibition of voltage-dependent Ca2+ influx into rod bipolar cell terminals.},
  author={Iona D'Angelo and Nicholas C Brecha},
  journal={Neuroscience},
  year={2004},
  volume={125 4},
  pages={1039-49}
}
Neuropeptide Y (NPY) is a potent inhibitory neuropeptide expressed by amacrine cells in the rat retina. NPY modulates the release of multiple neurotransmitters in mammalian retina, yet the mechanisms mediating this regulation are not well defined. To further understand the action of NPY in the retina, Y receptor coupling to voltage-dependent Ca(2+) channels was investigated using Ca(2+) imaging with fura-2 AM to measure [Ca(2+)](i) increases in rod bipolar cell terminals. Y receptor expression… CONTINUE READING

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