Y chromosome sequence variation and the history of human populations

  title={Y chromosome sequence variation and the history of human populations},
  author={P. Underhill and P. Shen and A. A. Lin and L. Jin and G. Passarino and W. Yang and E. Kauffman and B. Bonn{\'e}-Tamir and J. Bertranpetit and P. Francalacci and M. Ibrahim and T. Jenkins and J. Kidd and S. Mehdi and M. T. Seielstad and R. S. Wells and A. Piazza and R. Davis and M. Feldman and L. Cavalli-Sforza and P. Oefner},
  journal={Nature Genetics},
  • P. Underhill, P. Shen, +18 authors P. Oefner
  • Published 2000
  • Biology, Medicine
  • Nature Genetics
  • Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history. We used denaturing high-performance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious genealogy of 116 haplotypes, several of which display distinct… CONTINUE READING
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