Y chromosome haplotypes reveal prehistorical migrations to the Himalayas

  title={Y chromosome haplotypes reveal prehistorical migrations to the Himalayas},
  author={Bing Su and Chunjie Xiao and Ranjan Deka and Mark Seielstad and Daoroong Kangwanpong and Junhua Xiao and Daru Lu and Peter A. Underhill and Luca L. Cavalli-Sforza and Ranajit Chakraborty and Li Jin},
  journal={Human Genetics},
By using 19 Y chromosome biallelic markers and 3 Y chromosome microsatellite markers, we analyzed the genetic structure of 31 indigenous Sino-Tibetan speaking populations (607 individuals) currently residing in East, Southeast, and South Asia. Our results showed that a T to C mutation at locus M122 is highly prevalent in almost all of the Sino-Tibetan populations, implying a strong genetic affinity among populations in the same language family. Furthermore, the extremely high frequency of H8, a… 

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A predominantly Northern Asian-specific component in Qiangic populations, especially in maternal lineages is revealed, which is an admixture of the northward migrations of East Asian initial settlers with Y chromosome haplogroup D in the late Paleolithic age and the southward Di-Qiang people in the Neolithic Age.

Y‐chromosome O3 Haplogroup Diversity in Sino‐Tibetan Populations Reveals Two Migration Routes into the Eastern Himalayas

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The Himalayas as a directional barrier to gene flow.

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A Northeast Asian origin for the Himalayan populations with subsequent gene flow from South Asia into the Kathmandu valley and the Newar population is suggested, corroborating a previous Y-chromosome study.

Extended Y chromosome investigation suggests postglacial migrations of modern humans into East Asia via the northern route.

It is proposed that although the Paleolithic migrations via the southern route played a major role in modern human settlement in East Asia, there are ancient contributions, though limited, from THE AUTHORS, which partly explain the genetic divergence between current southern and northern East Asian populations.

Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations

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High Resolution Phylogeographic Map of Y-Chromosomes Reveal the Genetic Signatures of Pleistocene Origin of Indian Populations

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Admixed Origin of the Kayah (Red Karen) in Northern Thailand Revealed by Biparental and Paternal Markers

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Y-STR diversity in the Himalayas

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Polynesian origins: insights from the Y chromosome.

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    Proceedings of the National Academy of Sciences of the United States of America
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Southeast Asia provided a genetic source for two independent migrations, one toward Taiwan and the other toward Polynesia through island Southeast Asia, according to the Y-chromosome data.

Mitochondrial DNA analysis of Mongolian populations and implications for the origin of New World founders.

It is proposed that indigenous populations in east Central Asia represent the closest genetic link between Old and New World populations and is likely that founder effects manifest throughout Asia and the Americas are responsible for differences in mtDNA haplotype frequencies observed in these regions.

Y chromosome polymorphisms in Native American and Siberian populations: identification of Native American Y chromosome haplotypes

The detection of the T allele in all five Native American populations studied and in two of nine native Siberian populations suggested that the DYS199 T allele may have originated in Beringia and was then spread throughout the New World by the founding populations of the major subgroups of modern Native Americans.

Multiple origins of Tibetan Y chromosomes

It is concluded that Tibetan Y chromosomes may have been derived from two different gene pools, given the virtual absence of M122C in central Asia and YAP+ in east Asia, with drift an unlikely mechanism accounting for these observations.

Characterization of ancestral and derived Y-chromosome haplotypes of New World native populations.

The ancestral founder haplotype, 0A, of the DYS199T lineage is identified and it is proposed that 0A is one of the most prevalent founder paternal lineages of New World aborigines.

A pre-Columbian Y chromosome-specific transition and its implications for human evolutionary history.

The data suggest a single origin of linguistically diverse native Americans with subsequent haplotype differentiation within radiating indigenous populations as well as post-Columbian European and African gene flow.

Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age.

  • B. SuJ. Xiao L. Jin
  • Environmental Science
    American journal of human genetics
  • 1999
This pattern indicates that the first settlement of modern humans in eastern Asia occurred in mainland Southeast Asia during the last Ice Age, coinciding with the absence of human fossils in easternAsia, 50,000-100,000 years ago.

Ancestral Asian source(s) of new world Y-chromosome founder haplotypes.

The contrasting distribution patterns of the two major candidate founder haplotypes in Asia and the New World, as well as the results of a nested cladistic analysis, suggest the possibility of more than one paternal migration from the general region of Lake Baikal to the Americas.

The geographic distribution of human Y chromosome variation.

Variation on the nonrecombining portion of the human Y chromosome is examined to investigate human evolution during the last 200,000 years, compatible with a variety of hypotheses, including multiple human migrations and range expansions.

Genetic relationship of populations in China.

  • J. ChuW. Huang L. Jin
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1998
Genetic evidence does not support an independent origin of Homo sapiens in China, and it is more likely that ancestors of the populations currently residing in East Asia entered from Southeast Asia.