Y-box binding protein 1--a prognostic marker and target in tumour therapy.

@article{Kosnopfel2014YboxBP,
  title={Y-box binding protein 1--a prognostic marker and target in tumour therapy.},
  author={Corinna Kosnopfel and Tobias Sinnberg and Birgit Schittek},
  journal={European journal of cell biology},
  year={2014},
  volume={93 1-2},
  pages={61-70}
}
Y-box binding protein 1 (YB-1) is a multifunctional protein involved in various cellular processes including both transcriptional and translational regulation of target gene expression. Significantly increased YB-1 levels have been reported in a number of human malignancies and shown to be associated with poor prognosis and disease recurrence. Indeed, YB-1 can act as a versatile oncoprotein playing an important role in tumour cell proliferation and progression. Consequently, YB-1 not only… CONTINUE READING
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