Xylitol production by a Pichia stipitis D-xylulokinase mutant

  title={Xylitol production by a Pichia stipitis D-xylulokinase mutant},
  author={Yong-Su Jin and Jose Cruz and Thomas W. Jeffries},
  journal={Applied Microbiology and Biotechnology},
Xylitol production by Pichia stipitis FPL-YS30, a xyl3-Δ1 mutant that metabolizes xylose using an alternative metabolic pathway, was investigated under aerobic and oxygen-limited culture conditions. Under both culture conditions, FPL-YS30 (xyl3-Δ1) produced a negligible amount of ethanol and converted xylose mainly into xylitol with comparable yields (0.30 and 0.27 g xylitol/g xylose). However, xylose consumption increased five-fold under aerobic compared to oxygen-limited conditions. This… CONTINUE READING

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