Xylitol production at high temperature by engineered Kluyveromyces marxianus.

@article{Zhang2014XylitolPA,
  title={Xylitol production at high temperature by engineered Kluyveromyces marxianus.},
  author={Jia Zhang and Biao Zhang and Dongmei Wang and Xiaolian Gao and Jiong Hong},
  journal={Bioresource technology},
  year={2014},
  volume={152},
  pages={192-201}
}
Several recombinant Kluyveromyces marxianus strains were constructed through overexpressing the Neurospora crassa xylose reductase genes. YZJ015, which maintained the original xylitol dehydrogenase gene, produced xylitol with the highest productivity (1.49 g L(-1) h(-1)) from 100 g L(-1) xylose at 42 °C. Even at 45 °C, YZJ015 was still able to produce 60.03 g L(-1) xylitol from 100 g L(-1) xylose with a productivity of 1.25 g L(-1)h(-1). In addition, for 20 rounds of cell recycling at 42 °C… CONTINUE READING

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