Xylitol: A Review on Bioproduction, Application, Health Benefits, and Related Safety Issues

  title={Xylitol: A Review on Bioproduction, Application, Health Benefits, and Related Safety Issues},
  author={Salim Ur-Rehman and Zarina Mushtaq and Tahir Zahoor and Amira Hajirah Abd Jamil and Mian Anjum Murtaza},
  journal={Critical Reviews in Food Science and Nutrition},
  pages={1514 - 1528}
Xylitol is a pentahydroxy sugar-alcohol which exists in a very low quantity in fruits and vegetables (plums, strawberries, cauliflower, and pumpkin). On commercial scale, xylitol can be produced by chemical and biotechnological processes. Chemical production is costly and extensive in purification steps. However, biotechnological method utilizes agricultural and forestry wastes which offer the possibilities of economic production of xylitol by reducing required energy. The precursor xylose is… 
Microbial xylitol production.
All probable microbial xylitol production biochemical pathways encompassing diverse bioprocesses involved in uptake and conversion of xylose sugars from agricultural residues and industrial effluents are reported on.
Xylitol: Bioproduction and Applications-A Review
Various microorganisms that have been used to produce xylitol, the bioprocess parameters, and genetic modifications to increasexylitol yield have been reviewed, and the applications, benefits, and safety concerns to health have been discussed.
Biotechnological Production of Xylitol from Biomass
This chapter will explore biotechnological xylitol production from the selection and preparation of the raw material to fermentative process conditions, downstream strategies and future perspectives.
Biotechnological production of xylitol from agricultural waste
This review presents the main advances in the use of microorganisms, substrates, and process conditions for the biotransformation of agricultural residues to xylitol and the main advantages and disadvantages obtained by biotechnological routes compared to traditional chemical routes are discussed.
Production of Xylitol from Corn Biomass using Candida sp. As Microbial Agent
The results showed that corncob is a promising material to use in producing xylitol from lignocellulosic biomass using Candida sp.
Xylitol Bioproduction in Hemicellulosic Hydrolysate Obtained from Sorghum Forage Biomass
The biotechnological production of xylitol from sorghum forage biomass was evaluated and there was no significant difference among the three varieties with respect to the contents of cellulose, hemicellulose, and lignin, although differences were found in the hydrolysate fermentability.
Biovalorisation of crude glycerol and xylose into xylitol by oleaginous yeast Yarrowia lipolytica
To the best of the author’s knowledge, this study demonstrates for the first time the potential of using Y. lipolytica as a microbial cell factory for xylitol synthesis from inexpensive feedstocks and the results obtained are competitive with otherxylitol producing organisms.
Comprehensive strategies of Lignocellulolytic enzyme production from microbes and their applications in various commercial-scale faculties
Activities of anthropological organisms lead to the production of massive lignocellulosic waste every year and these lignocellulolytic enzymes plays crucial role in developing eco-friendly,
Evaluation of some lignocellulosic byproducts of food industry for microbial xylitol production by Candida tropicalis
It was concluded that detoxified and fortified chestnut shell hydrolysate could be a potential medium for xylitol production.


Current trends in biotechnological production of xylitol and future prospects
This review describes recent research developments on biological conversion of hemicellulosic biomass towards production of xylitol by taking advantage of power of biotechnology and identifies ways forward for improved enzymatic xylitor production to compete with current chemical processes.
A rare sugar xylitol. Part II: biotechnological production and future applications of xylitol
The biotechnological method of producing xylitol by metabolically engineered yeasts, Saccharomyces cerevisiae or Candida, has been studied as an alternative to the chemical method.
Microbial conversion of d-xylose to xylitol
Production of xylitol by yeasts.
This study deals with some aspects regarding xylose transport and metabolism within the yeast cell, and factors that can affect xylitol production.
Xylitol Production From Agricultural Wastes For Utilization In Dietetic Food
Xylitol was produced from four indigenous agricultural by-products including sugarcane bagasse, oat hulls, mongbean hulls and peanut hulls through fermentation to evaluate potential of local