Xtbx6r, a novel T-box gene expressed in the paraxial mesoderm, has anterior neural-inducing activity.

@article{Yabe2006Xtbx6rAN,
  title={Xtbx6r, a novel T-box gene expressed in the paraxial mesoderm, has anterior neural-inducing activity.},
  author={Shigeharu Yabe and Shunsuke Tazumi and J. Fujisawa-shi Yokoyama and Hideho Uchiyama},
  journal={The International journal of developmental biology},
  year={2006},
  volume={50 8},
  pages={
          681-9
        }
}
T-box proteins are important transcriptional regulators in animal development. We searched the Xenopus laevis expressed sequence tag (EST) database using zebrafish tbx24 (Ztbx24) as a query and found a sequence. We then obtained corresponding clones from a neurula cDNA library. This novel gene has a T-box showing 53% homology with Xenopus laevis tbx6 (Xtbx6) and 51% with Ztbx24 at the amino acid level and is relatively close to Xtbx6 indicated by alignment analysis. In situ hybridization showed… CONTINUE READING

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