Xp21 dystrophin and 6q dystrophin-related protein. Comparative immunolocalization using multiple antibodies.

Abstract

A protein of Mr 400 K and slightly lower Mr than Xp21 dystrophin was detected in skeletal muscle from patients with Duchenne muscular dystrophy by three antibodies raised against the midrod and C-terminal portions of chicken dystrophin, and by antibodies to dystrophin-related protein. Immunocytochemistry showed continuous sarcolemmal staining of Duchenne… (More)

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