Xp11.2 translocation renal cell carcinoma.

  title={Xp11.2 translocation renal cell carcinoma.},
  author={Henry B. Armah and Anil V. Parwani},
  journal={Archives of pathology & laboratory medicine},
  volume={134 1},
Xp11.2 translocation renal cell carcinomas (RCCs), a recently recognized distinct subtype, are rare tumors predominantly reported in young patients. They comprise at least one-third of pediatric RCCs, and only few adult cases have been reported. They are characterized by various translocations involving chromosome Xp11.2, all resulting in gene fusions involving the transcription factor E3 (TFE3) gene. In recent years, at least 6 different Xp11.2 translocation RCCs have been identified and… CONTINUE READING


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