XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm.

@article{Wright1989XlHbox8A,
  title={XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm.},
  author={Christopher V E Wright and Patrick N. J. Schnegelsberg and Eddy M De Robertis},
  journal={Development},
  year={1989},
  volume={105 4},
  pages={787-94}
}
We report the isolation of a new homeobox gene from Xenopus laevis genomic DNA. The homeodomain sequence is highly diverged from the prototype Antennapedia sequence, and contains a unique histidine residue in the helix that binds to DNA. The homeodomain is followed by a 65 amino acid carboxyterminal domain, the longest found to date in any vertebrate homeobox gene. We have raised specific antibodies against an XlHbox 8-beta-gal fusion protein to determine the spatial and temporal expression of… CONTINUE READING
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