Xk-related protein 8 regulates myoblast differentiation and survival.

@article{Kim2017XkrelatedP8,
  title={Xk-related protein 8 regulates myoblast differentiation and survival.},
  author={Go-Woon Kim and Gi-hoon Nam and In-San Kim and Seung-Yoon Park},
  journal={The FEBS journal},
  year={2017},
  volume={284 21},
  pages={
          3575-3588
        }
}
Xk-related protein 8 (Xkr8) is a scramblase and responsible for phosphatidylserine (PS) exposure on the cell surface in a caspase-dependent manner. Although PS exposure is found to be important for myotube formation during myoblast differentiation, the role of Xkr8 during myogenesis has not been elucidated. Here we show that Xkr8 contributes to myoblast differentiation. Xkr8 overexpression induced the formation of large myotubes during early differentiation, but this phenotype was not related… CONTINUE READING

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