Xiang-Qi-Tang and its active components exhibit anti-inflammatory and anticoagulant properties by inhibiting MAPK and NF-κB signaling pathways in LPS-treated rat cardiac microvascular endothelial cells.

@article{He2013XiangQiTangAI,
  title={Xiang-Qi-Tang and its active components exhibit anti-inflammatory and anticoagulant properties by inhibiting MAPK and NF-κB signaling pathways in LPS-treated rat cardiac microvascular endothelial cells.},
  author={Chang-liang He and Peng-fei Yi and Qiao-jia Fan and Hai-qing Shen and Xiao-lin Jiang and Qian-Qian Qin and Zhou Song and Cui Zhang and Shuai-Cheng Wu and Xu-Bin Wei and Ying-Lun Li and B Q Fu},
  journal={Immunopharmacology and immunotoxicology},
  year={2013},
  volume={35 2},
  pages={215-24}
}
Xiang-Qi-Tang (XQT) is a Chinese herbal formula containing Cyperus rotundus, Astragalus membranaceus and Andrographis paniculata. Alpha-Cyperone (CYP), astragaloside IV (AS-IV) and andrographolide (AND) are the three major active components in this formula. XQT may modulate the inflammatory or coagulant responses. We therefore assessed the effects of XQT on lipopolysaccharide (LPS)-induced inflammatory model of rat cardiac microvascular endothelial cells (RCMECs). XQT, CYP, AS-IV and AND… CONTINUE READING
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