Xenotransplantation for CNS repair: immunological barriers and strategies to overcome them.

@article{Brevig2000XenotransplantationFC,
  title={Xenotransplantation for CNS repair: immunological barriers and strategies to overcome them.},
  author={Thomas Brevig and Jan Holgersson and H{\aa}kan Widner},
  journal={Trends in neurosciences},
  year={2000},
  volume={23 8},
  pages={337-44}
}
Neural transplantation holds promise for focal CNS repair. Owing to the shortage of human donor material, which is derived from aborted embryos, and ethical concerns over its use, animal donor tissue is now considered an appropriate alternative. In the USA, individuals suffering from Parkinson's disease, Huntington's disease, focal epilepsy or stroke have already received neural grafts from pig embryos. However, in animal models, neural tissue transplanted between species is usually promptly… CONTINUE READING
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