Xenopus rhodopsin promoter. Identification of immediate upstream sequences necessary for high level, rod-specific transcription.

@article{Mani2001XenopusRP,
  title={Xenopus rhodopsin promoter. Identification of immediate upstream sequences necessary for high level, rod-specific transcription.},
  author={Shobana S. Mani and S Batni and Leigh Whitaker and S Chen and Gustav A. Engbretson and Barry E. Knox},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 39},
  pages={36557-65}
}
To understand the mechanisms that control the cell-specific visual pigment gene transcription, the Xenopus rhodopsin 5' regulatory region has been characterized in vivo using transient transfection of Xenopus embryos and transgenesis. The principal control sequences were located within -233/+41, a region with significant conservation with mammalian rhodopsin genes. DNase footprinting indicated seven distinct regions that contain potential cis-acting elements. Sequences near the initiation site… CONTINUE READING

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