Xenopus oocytes and the biochemistry of cell division.

  title={Xenopus oocytes and the biochemistry of cell division.},
  author={James L. Maller},
  volume={29 13},
The control of cell proliferation involves both regulatory events initiated at the plasma membrane that control reentry into the cell cycle and intracellular biochemical changes that direct the process of cell division itself. Both of these aspects of cell growth control can be studied in Xenopus oocytes undergoing meiotic maturation in response to mitogenic stimulation. All mitogenic signaling pathways so far identified lead to the phosphorylation of ribosomal protein S6 on serine residues… CONTINUE READING