Xenopus metamorphosis as a model to study thyroid hormone receptor function during vertebrate developmental transitions.


A hormone-dependent developmental transition from aquatic to terrestrial existence occurs in all tetrapod vertebrates, such as birth, hatching, and metamorphosis. Thyroid hormones (TH) and their receptors (TRs) are key players in the tissue transformations comprising vertebrate developmental transitions. The African clawed frog, Xenopus, is a premier model… (More)
DOI: 10.1016/j.mce.2017.03.020


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