Xenon incorporated in a lipid emulsion inhibits NMDA receptor channels.

@article{Weigt2003XenonII,
  title={Xenon incorporated in a lipid emulsion inhibits NMDA receptor channels.},
  author={Henry U Weigt and Michael Georgieff and Cordian Beyer and Ulrich Wachter and Karl Josef F{\"o}hr},
  journal={Acta anaesthesiologica Scandinavica},
  year={2003},
  volume={47 9},
  pages={1119-24}
}
BACKGROUND Over the past decade hyperpolarized (129)xenon incorporated in lipid emulsions has been studied for the purpose of imaging enhancement in radiology. Xenon (Xe), a NMDA (N-methyl-D-aspartate)-receptor antagonist, has neuroprotective properties even at subanesthetic concentrations. Thus, its intravenous administration for this purpose deserves further evaluation. In this study, we investigated in an in vitro model the effect of Xe, incorporated in a lipid emulsion (Lipofundin MCT(R) 20… CONTINUE READING