Xenon and nitrogen single-breath washout curves in patients with airway obstruction.

@article{Demedts1976XenonAN,
  title={Xenon and nitrogen single-breath washout curves in patients with airway obstruction.},
  author={Maurits M Demedts and Mathias de Roo and J Cosemans and L. Billiet and Karel P Van de Woestijne},
  journal={Journal of applied physiology},
  year={1976},
  volume={41 2},
  pages={185-90}
}
In patients with chronic obstructive lung disease, we determined single-breath N2 and 133 Xe washout curves, and regional distributions of volumes (Vr) and of 133Xe boluses inhaled at residual volume (VIRV). Patients suffering from emphysema with minimal airway obstruction demonstrated large closing volumes and apicobasal distribution gradients, apparently… CONTINUE READING