Xenon Misuse in Sports – Increase of Hypoxia-Inducible Factors and Erythropoietin, or Nothing but „Hot Air“?

  title={Xenon Misuse in Sports – Increase of Hypoxia-Inducible Factors and Erythropoietin, or Nothing but „Hot Air“?},
  author={W. Jelkmann},
  journal={Deutsche Zeitschrift Fur Sportmedizin},
  • W. Jelkmann
  • Published 2014
  • Medicine, Chemistry
  • Deutsche Zeitschrift Fur Sportmedizin
Experimental evidence suggests that xenon (Xe) is not completely inert but can affect the functional properties of proteins, particularly that of ion channels and of enzymes. According to recent reports xenon can activate the hypoxia-inducible transcription factors (HIF). A number of preclinical investigations (cell culture experiments, animal studies) has been performed concerning this, but the results have been volatile and the mechanism of HIF activation differed from that of hypoxia… Expand
5 Citations
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