Xenomelia: a new right parietal lobe syndrome

@article{McGeoch2011XenomeliaAN,
  title={Xenomelia: a new right parietal lobe syndrome},
  author={Paul D. McGeoch and David Brang and Tao Song and Roland R. Lee and Mingxiong Huang and Vilayanur S. Ramachandran},
  journal={Journal of Neurology, Neurosurgery \& Psychiatry},
  year={2011},
  volume={82},
  pages={1314 - 1319}
}
Background Damage to the right parietal lobe has long been associated with various disorders of body image. The authors have recently suggested that an unusual behavioural condition in which otherwise rational individuals desire the amputation of a healthy limb might also arise from right parietal dysfunction. Methods Four subjects who desired the amputation of healthy legs (two right, one left and one, at first, bilateral and then left only) were recruited and underwent magnetoencephalography… Expand
The desire for healthy limb amputation: structural brain correlates and clinical features of xenomelia.
TLDR
The predominantly right-sided cortical abnormalities are in line with a strong bias for left-sided limbs as the target of the amputation desire, evident both in this sample and in previously described populations with xenomelia. Expand
When having a limb means feeling overcomplete. Xenomelia, the chronic sense of disownership and the right parietal lobe hypothesis
TLDR
The presence of both structural and functional multi-layered brain abnormalities in xenomelia suggests a multifactorial aetiology; however, as the prevalence of correlational studies, causal relationships remain to be investigated. Expand
Parietal Lobe Reorganization and Widespread Functional Connectivity Integration in Upper-Limb Amputees: A rs-fMRI Study
  • Bingbo Bao, Haifeng Wei, +11 authors Xianyou Zheng
  • Medicine
  • Frontiers in Neuroscience
  • 2021
TLDR
The right parietal lobe appears to be involved in some aspect of body awareness and depression in amputation patients and Seed-based, whole-brain FC analysis revealed that FC in the ULA group significantly decreased in many brain regions across the entire brain. Expand
Brain activity elicited by viewing pictures of the own virtually amputated body predicts xenomelia
TLDR
Findings show that neuronal processing in response to pictures of one's own desired body state is different in Xenomelia compared with controls and might represent a neuronal substrate of the xenomelia complaints that become behaviourally relevant, at least when rating the pleasantness and attractiveness of one’s own body. Expand
White Matter Abnormalities in Body Integrity Dysphoria
TLDR
Previous results showing alterations in areas tuned to the processing of the sensorimotor representations of the affected leg, and to higher-order components of bodily representation such as the body image showed structural alterations as well are confirmed. Expand
White Matter Abnormalities in Body Integrity Dysphoria
TLDR
Previous results showing alterations in areas tuned to the processing of the sensorimotor representations of the affected leg, and to higher-order components of bodily representation such as the body image were confirmed and extended. Expand
Shape alterations of basal ganglia and thalamus in xenomelia
TLDR
The present study provides strong evidence for shape differences in striatal, pallidal, and thalamic subregions housing subcortical body part representations and adds to previously described neural correlates of a condition one can barely empathize with and invites future connectivity analyses in cortico-subcortsical networks. Expand
Brain Abnormalities in Individuals with a Desire for a Healthy Limb Amputation: Somatosensory, Motoric or Both? A Task-Based fMRI Verdict
TLDR
It is concluded that BID is associated with altered integration of somatosensory and, to a lesser extent, motor signals, involving limb-specific cortical maps and brain regions where the first integration of body-related signals is achieved through convergence. Expand
The Desire for Amputation or Paralyzation: Evidence for Structural Brain Anomalies in Body Integrity Identity Disorder (BIID)
TLDR
The results suggest that BIID is associated with structural brain anomalies and might result from a dysfunction in the integration of multisensory information, leading to the feeling of disunity between the mental and physical body shape. Expand
The antero-dorsal precuneal cortex supports specific aspects of bodily awareness.
TLDR
The present findings indicate a critical role of the antero-dorsal precuneus in specific aspects of bodily awareness and in the maintenance of body schema. Expand
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References

SHOWING 1-10 OF 42 REFERENCES
Spatial frames of reference and somatosensory processing: a neuropsychological perspective.
  • G. Vallar
  • Medicine
  • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 1997
TLDR
There is evidence that the sensory stimulations that modulate left somatosensory deficits affect left motor disorders in a similar, direction-specific, fashion and that these stimulations may improve or worsen a number of manifestations of the neglect syndrome. Expand
Somatoparaphrenia: a body delusion. A review of the neuropsychological literature
TLDR
Somatoparaphrenia is often brought about by extensive right-sided lesions, but patients with posterior (parietal-temporal), and insular damage are on record, as well as a few patients with subcortical lesions. Expand
Beyond re-membering: phantom sensations of congenitally absent limbs.
TLDR
A series of behavioral, imaging, and neurophysiological experiments with a university-educated woman born without forearms and legs indicate that body parts that have never been physically developed can be represented in sensory and motor cortical areas. Expand
Can vestibular caloric stimulation be used to treat apotemnophilia?
TLDR
It is suggested that there are clear similarities to be drawn between BIID and somatoparaphrenia and that a dysfunction of the right parietal lobe is also the cause of BIID. Expand
The Vestibular Cortex: Its Locations, Functions, and Disorders
Abstract: Evidence is presented that the multisensory parieto‐insular cortex is the human homologue of the parieto‐insular vestibular cortex (PIVC) in the monkey and is involved in the perception ofExpand
The perception of phantom limbs. The D. O. Hebb lecture.
TLDR
It is suggested that patients with phantom limbs provide a valuable opportunity not only for exploring neural plasticity in the adult human brain but also for understanding the relationship between the activity of sensory neurons and conscious experience. Expand
Anosognosia for motor and sensory deficits after unilateral brain damage: a review.
TLDR
It is made that anosognosia for sensory and motor neurological deficits should be considered as a multi-component syndrome, including a number of specific disorders that are due to the impairment of discrete monitoring systems, specific for the different supervised functions. Expand
Misoplegia: a review of the literature and a case without hemiplegia
TLDR
Brain damage may cause profound changes in people’s attitudes towards their own bodies, and altered limb perception includes asomatognosia (lack of awareness of a part of the body), somatoparaphrenia ( lack of ownership of a paralysed limb), the experience of supernumerary phantom limbs, personification, and misoplegia. Expand
Hemianopia, hemianaesthesia, and hemiplegia after right and left hemisphere damage. A hemispheric difference.
TLDR
It is suggested that left spatial neglect is the factor underlying this hemispheric difference in somatosensory, visual half-field and motor deficits contralateral to a hemispheres lesion. Expand
PROBLEM OF IMPERCEPTION OF DISEASE AND OF IMPAIRED BODY TERRITORIES WITH ORGANIC LESIONS RELATION TO BODY SCHEME AND ITS DISORDERS
TLDR
The phenomenon of nonperception of disease has been observed in patients with cortical blindness from bilateral lesion of the occipital lobe and in persons with visual field defects from cerebral hemiplegia. Expand
...
1
2
3
4
5
...